Urotrol is the NEJM (New England Journal of Medicine) recommend the highest level of drug for OAB treatment. Urotrol ingredients Propiverine HCl, each a dose of 15mg, similar treatment of overactive bladder drug Oxybutynin there Tolterodine and so on.
Urotrol has a dual pharmacological properties, including anticholinergic (Anticholinergic) and direct smooth muscle spasm (calcium channel blocking effect). Anticholinergic to inhibit the nerve to force urine muscle contraction effect, while calcium channel blocking effects of a direct role in the bladder antispasmodic.
Health Insurance approved indications:
- Incontinence
- Instability of the bladder state of urgency and urinary frequency.
Side effect: often occurs, or dry mouth and blurred vision. Less occurrence of gastrointestinal discomfort and fatigue.
Such overactive bladder drugs, Oxybutynin is the first use, but because the dry mouth side effects of too much, leading to more new drugs, because of the different pharmacological effects, known side effects of the minimum of Tolterodine can significantly improve dry mouth side effects, but unfortunately too expensive, so health insurance has many restrictions. The Urotrol a medical report the occurrence of dry mouth side effects are actually quite Telterodine. Urotrol and limitations of health insurance.
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- At Eur Urol.2005; 48 (3) :478-482 [ ↩ ]