益生菌probiotics,在醫學期刊有許多豐富的資料,我們如果在MEDLINE上打入”probiotics”一共有3569篇文章,多麼驚人的數字,我沒時間看.....

如果是probiotics+allergy 一共有255篇,(probiotics+urticaria也有三篇),probiotics+atopic也有121篇,可見益生菌在治療過敏或者是異位性皮膚炎,有一定的效果。

先找一篇2007年五月報告發表在The Journal of allergy and clinical immunology

2007 May;119(5):1174-80. Epub 2007 Mar 8.
Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trial.
BACKGROUND: An altered microbial exposure may underlie the increase of allergic diseases in affluent societies. Probiotics may alleviate and even prevent eczema in infants. OBJECTIVE: To prevent eczema and sensitization in infants with a family history of allergic disease by oral supplementation with the probiotic Lactobacillus reuteri. METHODS: Double-blind, randomized, placebo-controlled trial, which comprised 232 families with allergic disease, of whom 188 completed the study. The mothers received L reuteri ATCC 55730 (1 x 10(8) colony forming units) daily from gestational week 36 until delivery. Their babies then continued with the same product from birth until 12 months of age and were followed up for another year. Primary outcome was allergic disease, with or without positive skin prick test or circulating IgE to food allergens. RESULTS: The cumulative incidence of eczema was similar, 36% in the treated versus 34% in the placebo group. The L reuteri group had less IgE-associated eczema during the second year, 8% versus 20% (P = .02), however. Skin prick test reactivity was also less common in the treated than in the placebo group, significantly so for infants with mothers with allergies, 14% versus 31% (P = .02). Wheeze and other potentially allergic diseases were not affected. CONCLUSION: Although a preventive effect of probiotics on infant eczema was not confirmed, the treated infants had less IgE-associated eczema at 2 years of age and therefore possibly run a reduced risk to develop later respiratory allergic disease. CLINICAL IMPLICATION: Probiotics may reduce the incidence of IgE-associated eczema in infancy.

 

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