咖啡與乳癌的關係

咖啡是很多人的重要食物,當然價錢比便當還要貴,但是咖啡對身體有什麼傷害呢?我們來看一下這篇關於咖啡與乳癌的醫學報告。Br J Cancer. 1990 August; 62(2): 267–270.

Coffee consumption and the risk of breast cancer. A prospective study of 14,593 Norwegian women.

Abstract

The association between coffee consumption and the incidence rate of breast cancer has been analysed in 152 incident cases of breast cancer that developed among 14,593 Norwegian women during a mean follow-up of 12 years. 1 At the time of inquiry they were between 35 and 51 years of age, and at the end of follow-up between 46 and 63. There was an overall weak negative association between daily intake of coffee and risk of breast cancer, which was not statistically significant. However, the association with coffee varied, depending on the body mass index (BMI) of the women. In the lean (Quetelet less than 24; population mean) there was an inverse relation between coffee intake and risk of breast cancer (chi 2 trend = 5.07, P = 0.02). In this group, women who reported drinking 5 cups or more per day2 had an age-adjusted IRR of 0.5 (95% confidence intervals, 0.3 and 0.9) compared to women who had 2 cups or less. In women with Quetelet’s index equal to or greater than 24 there was a positive relation between coffee intake and breast cancer risk (chi 2 trend = 2.33, P = 0.13), where the corresponding age-adjusted IRR was 2.1 (95% confidence intervals, 0.8 and 5.2). This interaction effect between coffee intake and BMI was statistically significant (chi 2 interaction = 10.2, 3 d.f., P = 0.02). In summary, the results of this study suggest that coffee consumption reduces the risk of breast cancer in lean women, whereas coffee might have the opposite effect in relatively obese women. 

 

這篇文章到底重點是什麼呢?簡單來說,就是如果你的BMI大於25,每天千萬不要喝超過5杯咖啡,否則會大大提高乳癌的機率。

下一篇57健康同學會邀訪

  1. 觀察了14,593個案,一共花了12年的時間 []
  2. 一天喝五杯 []

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超級細菌可怕嗎?

最近超級細菌成為一個非常熱門的話題,寶島新聲剛好找我去談這個話題,才知道這個其實很老的話題,又造成了恐慌,記得在2002年美國已經發現了很可怕的細菌。當時就說連萬古黴素都無法治療的金黃色葡萄球菌已經出現了,提醒大家要注意,果然今年就出現了超級細菌。

超級細菌的暫定名稱是NDM-1(附註),由於已經攻陷全球10多個國家,衛生署疾病管制局正式公告,將「多重抗藥性腸道菌感染症」(New Delhi metallo-β- lactamase 1 Enterobacteriaceae,即NDM-1腸道菌感染症)列入第四類法定傳染病,目前台灣還沒有這種超級細菌的病例,因為並非空氣傳染,病人不必強制隔離。

這是第一個重點,超級細菌不會經過空氣傳染,所以不可能像Sars或者H1N1一樣,有這麼大的傳染力,所以民眾不用驚慌。

還有另外一個重點,NDM1超級細菌是腸道細菌,和大腸桿菌同屬,但只透過外科手術的接觸或器械傳染的腸道菌,患者不需強制隔離。

超級細菌鬧的沸沸揚揚,也不過只死了不到十個人,這樣需要我們惶惶不可終日嗎?

超級細菌出現的用意在於提醒民眾不可濫用抗生素,但是民眾完全不知道耶,從這篇文章可以看出:超級細菌襲亞洲,生技、防疫股全面大漲,就已經告訴你抗生素沒用,不會空氣傳染,請問這些股票漲個什麼碗糕?

人類必須搞清楚一件事情,人類是無法勝過上帝的,不要繼續想要建造巴別塔了,我們必須學習和細菌和平共處,抗生素的使用是否應該管制的更嚴格?包括診所和藥局,我建議應該將抗生素列為四級管制藥品,必須有處方簽才可以開立,衛生主管機關快點醒來啦!

老子說:聖人不死,大盜不止,如果抗生素一直研發,超級細菌不會停止的!

附註:其實NDM-1是一段細菌上的基因,但是目前暫時用來取代細菌的命名。

 

下一篇保肝錄音檔下載

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